Our lab studies the genetic pathways that cause inherited cardiomyopathies in humans in an effort to identify novel methods to prevent and treat hypertrophic cardiomyopathy and heart failure. We utilize a variety of experimental systems which include mammalian cell culture, vertebrate model organisms, and human samples.
The primary goals of the lab are:
- Identify novel pathways involved in the pathogenesis of inherited cardiomyopathies in humans.
- Develop methods to study these pathways using both in vitro and in vivo experimental model systems.
- Identify chemical modifiers of these disease pathways which can serve as the foundation for novel therapeutic strategies.