From bench to bedside, the Gumina Lab is deciphering the role of nucleotides in human cardiovascular disease.

Dr. Gumina is a Physician-Scientist (PhD-MD) Interventional Cardiologist with an active research program examining the role of extracellular nucleotide regulation in cardiovascular disease.

The laboratory is focused on understanding the molecular mechanisms that influence the levels of extracellular ATP, ADP and adenosine following vascular or myocardial injury.

The overall goal of this work is to understand how innate regulation of extracellular nucleotide/nucleoside metabolism controls normal cardiac physiology and modifies myocardial injury and healing in human pathology. With the insights gained through these investigations we will develop novel approaches, diagnostics and therapies to improve the treatment of patients with acute coronary syndromes and coronary artery disease.